Apoptosis and Oxidative stress

Apoptosis and Oxidative stress






My memories
Apoptosis and Oxidative stress
Posted in 2013


Oxidative stress is implicated between causes of male infertility. ROS production and its effects on semen quality have been widely clarified. Oxygen is essential to sustain life, and physiological levels of ROS are necessary to maintain normal cell functions. However, products of oxygen such as ROS can be detrimental to cell function and survival .
ROS are detrimental to sperm survival and function due to its adverse effects on sperm membrane and genetic material. High frequency of single- and double-stranded DNA breaks due to oxidative stress activates apoptosis by inducing cytochrome c and caspases 9 and 3. Disruption of inner and outer mitochondrial membranes results in release of cytochrome c, a protein which activates caspases and induces apoptosis. Mitochondrial exposure to ROS results in the release of apoptosis-inducing factor, which directly interacts with the DNA and leads to DNA fragmentation . Seminal oxidative stress, sperm DNA damage, and apoptosis constitute a unified pathogenic molecular mechanism in infertility. Therefore, apoptosis in semen could be a useful indicator of semen quality.



My advise
1...  Oxygen is important for our life.   Without oxygen we cannot survive
2...  Oxygen is important for digesting our food
3...  Oxygen is important for our brain, lungs and kidney function,, cleaning our blood etc..
4...  Oxygen is important for sperm health of the male
5...  Follow healthy food for your body and sperm health

Brought to U ....  http://successgain.us

Comments

Post a Comment

Popular posts from this blog

Possible Male fertility Problems

Image
Possible Male Fertility problems  My memories Possible Male Fertility Problems Posted in 2015  Sexually Transmitted diseases or other infections.  G enital infections such as chlamydia  and gonorrhea  can cause infertility in men. The infertility can often be resolved by treating the infection. Blockages, birth defects   , or physical damage . In  some cases, men are born with blockages in parts of the testicle or other abnormalities that prevent sperm from getting into the semen. Physical trauma to the testicles, prostate, and urethra can also result in fertility problems. Surgery can sometimes correct the problem. Retrograde ejaculation.  In  this disorder, semen doesn't come out of the penis  during ejaculation, but instead enters the bladder. It can be caused by diabetes , certain medications , and surgery to the bladder, prostate, or urethra. Genetic diseases .  Although it's rare, ge...
Read more

Reproduction of Human Beings - Male

Image
Reproduction of Human Beings - Male Brought to U.... http://successgain.us     and    http://successgain.info My memories Reproduction of Human Beings- Male Posted in 2013 Reproduction in human beings is by sexual reproduction where both the male and female gametes fertilize to give rise to an embryo. The fertilization of human embryo occurs inside the body of the female. Thus, it is called Internal Fertilization. Human Beings are viviparous organisms who give rise to Embryos directly instead of laying eggs. Let us understand a little more about the male and female reproductive organs and the process of fertilization in them. Male Reproductive System Testes:  Male humans have two testes. They are situated in a bag of skin known as the scrotum. Scrotum lies outside the pelvic cavity. Sperm Duct:  These are thin ducts that arise from the testes. Prostrate Gland:  This gland is an accessory gland in males which pours its secret...
Read more

World Health day...Beat Diabetes

Image
World Health day...Beat Diabetes Brought to U.... http://successgain.us     and    http://successgain.info My memories World Health day...Beat Diabetes Posted in 2016 World Health Day 2016:  6th April 2016 is World Health Day...World Health Organization focused on Diabetes this year because the statistical data of Diabetes is increasing rapidly... At present,  type 1 diabetes  cannot be prevented. The environmental triggers that are thought to generate the process that results in the destruction of the body’s insulin-producing cells are still under investigation. While there are a number of factors that influence the development of  type 2 diabetes , it is evident that the most influential are lifestyle behaviours commonly associated with urbanization. These include consumption of unhealthy foods and inactive lifestyles with sedentary behaviour. Studies from different parts of the world have established that  lifestyle modif...
Read more